The Workshop will be part of the 43rd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society (EMBC 2021) and will be held virtually on Saturday, October 30, 2021 – 7:30AM – 1:00PM CDT.
Synopsis: The Brain-Machine Interface (BMI) is a thriving and rapidly expanding field. BMIs have been developed during the recent years for people with severe disabilities to restore function or improve their quality of life. Moreover, closed-loop, bidirectional brain-to-machine (BMI) and machine-to-brain (MBI) feedback systems have recently been developed and extended to incorporate related research areas, such as rapid functional mapping on the cortical level, and rehabilitation & therapy after disabling injuries. This novel BMI/MBI paradigm holds the promise of bringing major improvements in the restoration of motor and somatosensory function. The MBI stream of the BMI/MBI paradigm, typically used for encoding sensory feedback to the brain has seen recent significant progress, paving the way to a new generation of neuroprostheses with closed-loop capabilities. Furthermore, neurorobotics applications, which fuse robotics, neuroscience and artificial intelligence, enable the expansion of BMI/MBI by providing a platform to validate neuroscientific models, as well as opening the possibility of developing seamlessly integrated artificial limbs, which function as complex machines, thus providing enhanced embodiment and functionality.
The goal of this workshop is to discuss latest advances and challenges on the pathway to translational BMI/MBIs and neurorobotics for neurorehabilitation. Speakers will present research work and state-of-the-art, addressing the challenges of (i) real-time neural decoding and encoding, (ii) technological advances for interfacing with the peripheral and central nervous system, (iii) neuromodulation paradigms, covering invasive and noninvasive solutions, (iv) tools for cortical mapping of sensorimotor function, (v) theoretical models and tools supporting translation efforts.
The participants are expected to be rising graduate students and post-doctoral fellows. Additional academic researchers are encouraged to participate as well to develop and participate in collaborative networks. The workshop will conclude with an expert panel discussion highlighting challenges and opportunities as well as expected future developments in the field.
Reference and reading material will include The Handbook of Neuroengineering (Springer-Nature, to be published) and papers/reviews contributed by the presenters.
- 7:30-7:40AM Opening Remarks: Nitish Thakor and Andrei Dragomir
Brain-Machine Interface (Cortical/Intracortical) Theme
- 7:40 - 8:00AM Cynthia Chestek (University of Michigan) Amplifying Signals from Individual Nerve Fascicles
- 8:00 - 8:20AM Bolu Ajiboye (Case Western) Neural Representation of Observed, Imagined, and Attempted Grasping Force in Motor Cortex of Individuals with Chronic Tetraplegia
- 8:20 - 8:40AM Flavia Vitale (UPenn) Novel Material and Manufacturing Approaches for Neural Interfaces
Machine-Brain Interface: Sensory Restoration and Augmentation Theme
- 8:40 - 9:00AM Tamar Makin (University College London) Neurocognitive Opportunities and Limitations of Hand Augmentation
- 9:00 - 9:20AM Stanisa Raspopovic (ETH) Advancing Bi-directional Limb Neural Prostheses
- 9:20 - 9:40AM Max Ortiz-Catalan (Chalmers University) Chronic Use of Neuromusculoskeletal Prosthetic Hands with Neural Control and Sensory Feedback
- 9:40 - 10:00AM Chad Bouton (Northwell Health) Rerouting and Restoring Neural Signals in Paralysis for Enabling Motor and Sensory Function
- 10:00 - 10:20AM Dustin Tyler (Case Western Reserve University) - Future directions in human machine interface
Closing the Loop Theme
- 10:20 - 10:40AM Maryam M. Shanechi (USC) Dynamic Brain Network Modeling and Decoding for Closed-Loop Neuromodulation of Mental States
Neurorobotics and Exoskeletons Theme
- 10:40 - 11:00AM Gordon Cheng (Technical University of Munich): Neuroengineering Challenges of Fusing Robotics and Neuroscience
- 11:00 - 11:20AM Jose Contreras Vidal (University of Houston) - Motor Recovery Following Brain-Exoskeleton Interface Mediated Stroke Rehabilitation
Young Investigator Theme
- 11:20 - 11:35AM Luke Osborn (Johns Hopkins University, Applied Physics Lab) Bilateral Intracortical Microstimulation for Sensory Feedback
- 11:35 - 11:50AM Emily Graczyk (Case Western Reserve University) Development of Novel Neurostimulation Paradigms by Leveraging Computational Models and Artificial Intelligence
- 11:50 - 12:05PM Hunter Schone (UCL/NIH) Is the Human Body the Ultimate Design Template for Artificial Limbs?
- 12:05 - 12:20PM Tessy Thomas (UT Health Science Center) Decoding Sensorimotor Representations of Upper-limb Joint Movements from Different Spatial Resolutions of Cortical Recordings
- 12:20 - 12:25 Synopsis (Nitish Thakor)
- 12:25 - 1:00PM Expert Panel Discussion and Q&A Session with Audience
Moderators: Nitish Thakor, Dustin Tyler, Gordon Cheng
Dr. Ajiboye’s main research interest is in the development and control of brain-computer-interface (BCI) neuroprosthetic technologies for restoring function to individuals who have experienced debilitating injuries to the nervous system, such as spinal cord injury and stroke. Currently, he is interested in understanding the relationships between the firing patterns of multi-neuronal networks and the kinetic and kinematic outputs of these neural systems in the control of upper limb movements.
Dr. Bouton’s work has been featured on 60 Minutes and TEDx, and he holds over 70 patents worldwide. He has been awarded two R&D 100 Awards and was recognized by the US Congress for his work in the medical device field. He has been named Inventor of the Year and Distinguished Inventor by Battelle, and was selected by the National Academy of Engineering in 2011 to attend the Frontiers in Engineering Symposium.
Dr. Gordon Cheng has made pioneering contributions in Humanoid Robotics, Neuroengineering, Artificial Intelligence for the past 20 years. Since 2010, Gordon Cheng has been holding the Chair for Cognitive Systems, which he also founded. The Chair for Cognitive Systems is part of the Department of Electrical and Computer Engineering at Technical University of Munich (TUM), Munich/Germany.
Dr. Chestek’s research focuses on brain machine interface (BMI) systems using 100 channel arrays implanted in motor and pre-motor cortex. The goal of this research is to eventually develop clinically viable systems to enable paralyzed individuals to control prosthetic limbs, as well as their own limbs using functional electrical stimulation and assistive exoskeletons.
Dr. Makin's main interest is in understanding the key drivers and limitations of reorganisation in the adult brain. Her primary model for this work is studying individuals with a hand loss. A particular focus is on how habitual behaviour, such as prosthesis usage, shapes brain reorganisation. For this purpose, Dr. Makin's work integrates methods from the fields of neuroscience, experimental psychology and rehabilitation.
Dr. Ortiz Catalan's research focuses on bionics and due to sensorimotor impairment. This involves neural engineering, osseointegrated implants, neuromuscular interfaces, neurostimulation, bio-electric signals acquisition and processing, and machine learning for the decoding of motor volition. He is also interested in neuromuscular rehabilitation and the study and treatment of neuropathic pain due to sensorimotor impairment.
Dr. Raspopovic' main interest is focused on the development of innovative devices for treatment of neurologically disabled persons. In particular he develops mechatronic systems directly interfacing the environment with the residual nervous system, based on the exact hybrid computational modelling. Dr. Raspopovic is the 2021 grand prize winner of the Science & PINS Prize for Neuromodulation.
Dr. Shanechi works at the interface of machine learning, statistical inference and signal processing, and control to develop algorithmic solutions for basic and clinical neuroscience problems. Some applications of interest include developing closed-loop brain-machine interfaces (BMI) for motor function and for deep brain stimulation to treat neuropsychiatric disorders. Her work combines methodology development with in vivo implementation and testing.
Dr. Tyler is the Kent H. Smith Professor II in Biomedical Engineering at Case Western Reserve University in Cleveland, OH and Director of the Human Fusions Initiative. He is an expert in the science and technology of directly communicating with the human nervous system to create a symbiotic relationship between humans and technology. He has a secondary appointment as a principal investigator at the Louis-Stokes Cleveland Department of Veterans’ Affairs Medical Center (LSCDVAMC).
Dr. Contreras-Vidal's research focuses on 1) Reverse engineering the brain through computational studies; 2) Designing non-invasive brain-machine interface to robotic systems for rehabilitation, enhancement or repair of the motor system after injury, neurological insults, or advanced aging; 3) Utilizing neural interfaces as tools for reverse-translational studies of brain plasticity and brain-machine interaction/confluence; and 4) Developing bio-robotics and powered wearable exoskeletons.
Dr. Vitale is an Assistant Professor of Neurology and Physical Medicine & Rehabilitation at the University of Pennsylvania. Her research interests focus on flexible bioelectronic materials and devices for high-resolution, minimally invasive neural recording and stimulation. Dr. Vitale has authored more than 15 peer-reviewed journal and conference publications and is a co-inventor on six patent applications.
Dr. Emily Graczyk is an Assistant Professor in the Department of Biomedical Engineering at Case Western Reserve University and an Investigator in the Advanced Platform Technology Center at the Louis Stokes Cleveland VA Medical Center. Dr. Graczyk’s research examines the coding and processing of somatosensory information and the perceptual and psychological experience of artificial sensation created by neurotechnology.
Dr. Osborn is a Senior Professional Research staff at the JHU Applied Physics Laboratory at Johns Hopkins University Applied Physics Laboratory. His research area is in neuroengineering and applied neuroscience, which includes tactile sensing and feedback for sensory augmentation with focus on restoring sensation for rehabilitation.
Hunter Schone is a neuroscientist passionate about harnessing our understanding of the human body to promote successful human-machine interactions. By studying changes in the brain (fMRI) and behavior, his work examines the link between skill acquisition and brain plasticity. The ultimate goal being to help develop the next generation of human-centered technology. Hunter's research interests are at the crossroads of neuroscience, technology, and rehabilitation.
Dr. Tessy Thomas is a postdoctoral research fellow at the University of Texas Health Science Center at Houston. Her research investigates the neural correlates of upper-limb motor control and speech motor functions, with a focus on developing brain-machine interfaces to restore these functions to paralyzed individuals.
Dr. Thakor is a professor of biomedical engineering and neurology at the Johns Hopkins University School of Medicine. He also has an appointment in the Johns Hopkins Department of Electrical and Computer Engineering. He conducts research on neurological instrumentation, biomedical signal processing, micro and nanotechnologies, neural prosthesis, clinical applications of neural and rehabilitation technologies, and brain-machine interface.
Dr. Dragomir is currently a Senior Research Fellow at the N.1 Institute for Health, National University of Singapore. His research interests include sensory perception ranging from tactile and pain perception to olfaction. Further interests include cognitive assessment in neuroergonomics and brain-machine interaction. To investigate these, he uses neuroimaging techniques (EEG, fMRI) and develops tools for modeling and analyzing brain data based on network science and machine learning.
SINAPSE Laboratory, The N.1 Institute for Health
28 Medical Dr. #05-COR Singapore 117456
National University of Singapore